After a long time, there has been a new Beta update for Spybot Search & Destroy anti-spyware software with support for Microsoft Windows Vista.

New improvements/changes include:

Scanning engine
The methods available to detect malware have been more than doubled, including new ways to generically detect malware mutations.

TeaTimer
TeaTimer now automatically allows any changes during the installation of other security software which follow the ASCs guideline of code-signing all files, as well as a much improved scan of the files associated with registry changes

Integration with Windwos Vista Security Center
The Windows Security Center included with Windows Vista has a dedicated entry for malware protection software. Microsoft ships Windows Defender with Vista, however, Spybot-S&D can now easily integrate into the Vista Security Center; which will then monitor if Spybot-S&D is up-to-date and whether the permanent protection (TeaTimer) is running or not. This update will only show on Windows Vista.

First download the full version 1.4 and then install the 1.5 Beta upgrade since this Beta install only includes the components mentioned above.

Download links-

Version 1.4 full here or here
Version 1.5 Beta (with Vista integration) here